Institution | Faculty of Medicine - Walther Straub Institute of Pharmacology and Toxicology |
Remuneration group | TV-L E3 |
Full-time / Part-time | Part-time (65%) |
Start date | as soon as possible |
Application deadline | 2024-12-31 |
As part of the Research Training Group “Targets in Toxicology - Deciphering therapeutic targets in lung toxicology” (GRK 2338), we are offering a PhD position focusing on lung biology. The structured Ph.D. program (Ph.D. in Medical Research) combines highly interdisciplinary research projects with specialized training in the pathophysiology of the lung and the entire discipline of toxicology through an internationally renowned research network. The aim of the Research Training Group is to train a new generation of highly qualified toxicologists. Further information about the Research Training Group GRK 2338 can be found on our website.
Unlike an individual doctorate, the Ph.D. program offers a fixed curriculum (180 ECTS) with individual supervision, a fixed duration (three years) and regulated funding.
Research project: Identification of interaction partners of the pro-inflammatory P2X7 receptor by proximity labeling
This research project aims to identify the molecular mechanisms of P2X7 receptor signaling and its involvement in immune cell function and lung diseases. The P2X7 receptor is an ATP-gated ion channel and key mediator of inflammation. Its activation results in a variety of effects (e.g. cytokine secretion, cell morphology changes, apoptosis) that are incompletely understood (Kopp et al. Front. Mol. Neurosci.) In the proposed project we aim to generate, validate and use Turbo-ID-fused P2X7 receptors to identify components of the P2X7 signaling complex that mediate this effect.
We are looking for you:
in Munich
The successful applicant will
We offer:
People with disabilities who are equally as qualified as other applicants will receive preferential treatment.
If you have questions concerning the Research Training Group GRK 2338, please contact the program coordinator Steffi Resenberger. For more information about the research project, please contact Professor Dr. phil. nat. Annette Nicke.
Please submit the following documents to S.Resenberger@lmu.de until 31.12.2024:
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