|Institution||Faculty of Medicine - Max von Pettenkofer-Institut der Ludwig-Maximilians-Universität München|
|Full-time / Part-time||Full-time (100%)|
|Start date||Starting in early 2023|
The Department of Virology (chair: Prof. Oliver T. Keppler) of the Max von Pettenkofer Institute at LMU Munich offers a PhD Position in tumor chemosensitization starting in early 2023 in the laboratory of Prof. Oliver T. Keppler.
We have reported the role of the triphosphohydrolase SAMHD1 as a determinant of chemoresistance in acute myeloid leukemia (Nat. Med. 23(2):250-255 (2017); Nat. Commun. 10(1):3475 (2019); Commun. Biol. 3(1):324 (2020)). We have recently identified small molecule inhibitors of SAMHD1 that chemosensitize leukemic blasts and highly malignant solid tumors to specific nucleoside analogs. We employ state-of-the art molecular, biochemical and immunological approaches to explore the activity of these inhibitors in cell lines, primary cells, organotypic tumor cultures and small animal models.
We expect a strong interest in translational, interdisciplinary oncology, the ability to perform creative and independent research, and a high level of motivation.
The successful candidate will have a strong track record. Previous work with primary cells, molecular biology and biochemistry will be of advantage.
We offer interesting research topics with high biomedical relevance in a stimulating and interactive scientific environment at an internationally competitive level. The research campus in Großhadern/Martinsried offers a world-class scientific environment and access to core facilities.
Also possible in a part-time capacity.People with disabilities who are equally as qualified as other applicants will receive preferential treatment.
Please send your applications with full CV including list of publications, letter of motivation, and references until 31.12.2022 to email@example.com.
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